Cellular and Molecular Changes in Orthodontic Tooth Movement

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Cellular and Molecular Changes in Orthodontic Tooth Movement

Tooth movement induced by orthodontic treatment can cause sequential reactions involving the periodontal tissue and alveolar bone, resulting in the release of numerous substances from the dental tissues and surrounding structures. To better understand the biological processes involved in orthodontic treatment, improve treatment, and reduce adverse side effects, several of these substances have ...

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Molecular Biology of Orthodontic Tooth Movement

The application of orthodontic forces to correct mandibular and maxillary teeth irregularities through alveolar bone remodeling involves a series of coordinated and regulated molecular and cellular events in the periodontium i.e. periodontal ligament (PL), alveolar bone (AB), cementum, and gingiva. The PL and AB are the two important structures which actively participate in bone remodeling in r...

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Effect of Ovariectomy on Orthodontic Tooth Movement in Rats

Background and Aim: Estrogen affects the metabolism in females. This study aimed to assess the effect of absence of estrogen on orthodontic tooth movement in rats. Materials and Methods: In this animal study, 55 rats were randomly divided into four groups. Group 1 (n=10) had intact ovaries. In group 2 (n=15), ovaries were intact but the rats were subjected to stress due to tooth preparation. I...

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The effect of caffeine on orthodontic tooth movement in rats

Objective(s): to determine the effect of different doses of caffeine on orthodontic tooth movement (OTM) in rats. Materials and Methods: Forty male 250-300 g Sprague-Dawley rats were randomly divided into four groups of ten animals each and received 0 (control), 1 g/l, 2 g/l and 3 g/l caffeine in tap water for 3 days. Orthodontic appliances were ligated between the maxillary first molars and in...

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The tissue, cellular, and molecular regulation of orthodontic tooth movement: 100 years after Carl Sandstedt.

The first experimental investigation of orthodontic tooth movement was published by Sandstedt in 1904-1905. After 100 years, there is a good understanding of the sequence of events at both tissue and cellular levels and now the current focus of research is at the molecular level. The techniques of reverse transcription-polymerase chain reaction and in situ hybridization to detect mRNAs of inter...

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ژورنال

عنوان ژورنال: The Scientific World JOURNAL

سال: 2011

ISSN: 1537-744X

DOI: 10.1100/2011/761768